Veterinary Medicine: Neuropathology

Olivopontocerebellar degeneration associated with 3-hydroxy-3-methylglutaric aciduria in a domestic shorthair cat

Conclusion This is the first report of 3-hydroxy-3-methylglutaric aciduria in the veterinary literature. The two cats from the same litter presented at 3–6 months of age with progressive spinocerebellar signs and weakness. The female cat developed cerebellar signs in the late stage of the disease and urinalysis revealed significant elevations in 3-hydroxy-3-methylglutaric acid. The cat was […]