Partial cytogenetic response with toceranib and prednisone treatment in a young dog with chronic monocytic leukemia

Publication date 20th December 2013
Authors . Perez ML, Culver S, Owen J, Dunbar M, Kow K, Breen M, Milner


Treatment of chronic monocytic leukemia (CMoL) in dogs has traditionally consisted of hydroxyurea. The use of tyrosine kinase inhibitors has been proposed as a treatment option for dogs with CMoL but has never been reported. We report a case of CMoL in a young dog that achieved clinical remission with treatment with the tyrosine kinase inhibitor toceranib and prednisone.