Summary The relationship between radiographic measures of severity of osteoarthritis (OA) and changes in gene expression in joints are not well characterised. In this study, the expression of 11 candidate genes was characterised by quantitative reverse transcriptase polymerase chain reaction in normal and OA cartilage and bone from the elbows of dogs with fragmented coronoid […]
Veterinary Medicine: Dog Diseases/pathology
Comparison of bone mineral density in medial coronoid processes of dogs with and without medial coronoid process fragmentation
Objective To quantify bone mineral density (BMD) in the medial coronoid process (MCP) of dogs with and without fragmented medial coronoid processes (FMCPs) by use of dual- energy x-ray absorptiometry. Animals 50 osteochondral samples from 31 dogs that underwent subtotal coronoid ostectomy for unilateral or bilateral FMCP and 10 control osteochondral samples of the MCP […]
Histomorphometry of Fragmented Medial Coronoid Process in Dogs: A Comparison of Affected and Normal Coronoid Processes
Objective To determine if fatigue microdamage is associated with fragmented medial coronoid process (FMCP). Study design Prospective study. Animals Thirty-eight dogs were admitted for subtotal coronoid ostectomy as treatment for FMCP. Surgical specimens of medial coronoid process (MCP) were retrieved from treated dogs. Normal MCP were collected from 5 age- and breed-matched dogs and 2 […]